Vie CONG. INTERN. REPROD. ANIM. INSEM. ARTIF., PARIS, 1968, VOL. I based on the principles used in the treatment of gilts, It was considered advisable to apply a preliminary seven-day treatment with methallibure to inhibit any follicular activity which might be out of phase with the follicular maturation to be stimulated by PMS treatment, It had been noted previously that the mean interval to oestrus was significantly shorter after weaning than was the case in cycling animals after methallibure treatment, Therefore to maintain control over the time of ovulation it was decided to shorten the interval between PMS and HCG to 72 hours in the lactating sows, Because ovulation rates are higher in weaned sows than in gilts the dose of PMS was raised to 1000 i,u. Although the results of the experiments indicate very satisfactory responses to the treatments used, controlled experiments are required to establish the optimum dosage and timing of methallibure and supplementary gonadotrophin treat= ments in the newly weaned sow, All treatments using PMS tended to increase litter-size, suggesting that a modifica= tion of the techniques used might allow a significant increase to be obtained, Table I, Oestrus and fertility in treated pigs. Group |No, of | Days to Farrowing Litter- pigs oestrus inseminated (Mean) During | During 3 days | 1 day 6e 25(a) 43(e) 5,28(b) 100(£)* 4,91(c) 40(g) 4,96(c) 38(g) 4,02(d) 60(h) 4,33(d) 100(n)* Significantly ) (a) vs, (b), (c) vs, (d) different (e) vss (£), (g) vs, (h) P € 0,001 *Insemination on fixed=day, 1451