DBook II Sy PHILIS 1593 thickest part of the contagion coagulated in certain localities and formed gummata. "TThis contagion was not very readily taken in by the body, because of the viscosity in which its germs had been buried; hence there was needed a sort of reciprocal heat in two bodies; thus somehow the germs became active, and were able to ad— here to something else and to propagate themselves on nour— ishment analogous with themselves, but this, being as it were coagulated, they could not have done unless they had been heated. This is also the reason why the contagion remained latent for so long in the body before it manifested itself unmistakably. On account of the coldness and density of its substance, it would ereep on sluggishly, but presently would eat its way out and attack the solid parts of the body also, because of the sharpness (virulence) of the germs when they became active in that thick substance, and putrefaction began its work. First small ulcers appeared on the sexual organs, because it was in that locality and mainly from sexual intercourse that the contagion had its origin and beginning. 'These ulcers were not easy to deal with, partly because that locality is per se rather unclean, partly because, since the germs were dispersed hither and thither, when one part yielded to remedies and healed, in another part an ulcer would sprout forth. A reason why the pustules very often invaded the hairy scalp first is that that part of the body is somehow analogous with the contagion on account of the foulness and density of the humor by which it is nourished; another reason is that what evaporates from it rises upwards, and in every putrefaction much evaporation occurs. In cases where there were many pustules the pains were less severe, be— eause a great quantity of substance was being expelled, and at the same time this was a sign that the substance was more subtile. On the other hand, when the substance was more densely compacted, there were many violent attacks of pain and the pustules were fewer. 'The substance that caused the pains was not established in the aetual joints, because it was too dense to be able to penetrate to the joints and therefore settled for the most part above the nerves and muscles. 'The pain was felt more at night and at sunset because in the daytime the natural heat makes for the outer surfaces and the members that are usually in motion; for nature demands this heat in