Book II Sy PHILIS 147 bygone ages we must believe it was observed by our ancestors. There are in fact many proofs of this still extant. A certain barber, a friend of mine, had in his possession & small and very old book in which were certain prescriptions. Now among others there was one prescription entitled ^For use in the thick form of Scabies that is accompanied by Pains in the Joints'. Accordingly, when this disease first appeared and was still entirely novel, he remembered that remedy and consulted certain doctors as to whether he ought to use it in that new contagion, which he thought was identical with 'thick scabies'. But the doctors, after inspecting the remedy, em— phatically forbade him to use it, because it was compounded of quicksilver and sulphur. He would have been a lucky man if he had not consulted those doctors, for he would have made profits beyond belief and become a rich man. However he obeyed them, and did not dare to use the remedy. But finally he did try it, recognised that it was the best possible, and was deeply chagrined that he had not employed it until so late, for his profits had by that time been snatched from him by others. We can surely see from this that this disease had appeared 'in former times as well as in our own. In fact some authorities believe that Avicennas5' also was referring to syphilis when, under the heading 'Olibanum'/5? he said that incense mixed with vinegar and oil and used as an ointment is good for a cer— tain pain. ^I mean'", said he, "the pain that is accompanied by warts of a sort, which break out on the body and seem to run about like ants". However, that remark is not to the point, for Avicenna is there merely translating what Dioscurides writes5s 'On Incense!, where he says: *In the early stage, compounded as an ointment with vinegar and pitch, it removes ant—like warts and impetigo?'. Dioscurides here means the disease called ^Myrmecia?.54 TTo return to my subject, we must classify French Sickness as a new disease, and as one of a class that seldom manifest themselves. It follows that its causes and principles (primary agents) must be such as seldom arise. Moreover these causes and principles must be such that they are common not only to many human beings, but also to many parts of the world. Buch conditions can be referred to no other cause than the constitu— tion of the air. We must now enquire what was the nature of this constitution, and from what principles it arose.