Book II SV PHILIS 145 lieved that this contagion was carried to us from the New World which was discovered by the Spanish voyages, for there this malady is extremely prevalent. In proof of this, they point to the fact that this disease first appeared among us in Italy at the very time when that voyage had been made and trading had been carried on with the people of that country. For this reason too, they say, it was first observed among the Spaniards. Accordingly, they think that in all cases this malady depends on a contagion transmitted by one person to another. But, as & matter of fact, although the majority of those who have contraeted this disease have done so through contagion, never— theless it has been observed that countless others have been infected without any contagion per se. Moreover, it would have been impossible that this contagion, which per se is slow to aet and is not easily received, should have traversed so much of the world after having been first conveyed to the Spanish by a single fleet of ships. For it is well known that at the same time, or nearly the same, it was observed in Spain, France, Italy, Germany, and almost all Scythia.48 Consider also the fact that astronomers predicted its coming some years before it arrived, which goes far to prove that it has some other under— lying principle than simple and direet contagion. Now, in the first place, we ought not to be surprised that novel and un— usual diseases appear at certain times, diseases not conveyed from one country to another, but arising from their own peculiar causes. For instance, in the year 1482 there broke out a cer— tain kind of pleurisy which affected almost the whole of Italy. And in our own times there have appeared in Italy those fevers never before observed there, which are called enticulae?, and have been described above. Also, in bygone years, we have observed a contagious ophthalmia that attacked certain countries; again, we have seen that pest which is prevalent among cattle only and is recorded above.*? Hence it ought not to surprise us that the French Sickness also, though not previously known to our continent for many centuries, has now broken out for the first time. There will come yet other new and unusual ailments, as time brings them in its course; just as mentagra appeared among the ancients and has never since appeared again.ss* And this disease of which I speak, this syphilis too will pass away and die out, but later it will be born again and be seen again by our grandchildren, just as in