CHAPTER VII THE CAUSES OF THESE FEVERS All these phenomena were known to the public and lay open to the eye. But as to their causes and how they came to pass, there was great disagreement and dispute among the doctors, and various theories were held. Some asserted that an acute inflammatory condition was the cause, others plethora (of the humors), others intranspiration of bodies,?' others alleged some occult property. Hence each doctor applied his own rem— edies in accordance with his theory, which led to jesting at the expense of our profession, because so much disagreement could not be concealed from the public. But since these fevers were wide—spread, and were common to many persons at the same time, we must conclude that they had at that time a common cause, and that it was mainly contracted from the air, which seems reasonable enough. For, in the year 1528, there was first a winter of south winds and much rain, and in the spring many rivers overflowed their banks, with us, for instance, the Adige and the Po, and others elsewhere. At the same time there were mists which shrivelled most of the buds on the trees, especially the olives. From these causes we may believe that the principle (primary agent) of these fevers arose. But those which now appear sporadically have their special cause in our— selves in whom they first occur, and they take on a putrefaction of the same sort and exactly like that putrefaction which original— ly was common to many persons and had its origin in the air. Now this contagion, in comparision with those that are truly pestilent, seems rather mild, and is not contracted quickly, does not leave fomes behind, and is not carried to a distant object, but works slowly and only through actual handling of a sick person. We must therefore conclude that its germs are not very keen, and that they have not the strong and well—worked combination described above, but are more suited to be altered easily, and not to adhere, as others do which leave fomes be— 105