Book I CONTAGION 57 those which in our time have appeared in Italy and are called by some 'lenticulae', by others 'puncticulae!.38 I will mention also an unusual contagion which, in the year 1514, attacked cattle only, first observed in the district of Friuli; then gradually it was carried to the Euganeans, and thence to my own countryside.3? At first the cattle abstained from food, for no manifest reason. But when the herdsmen looked into their mouths they saw a sort of roughness and small pustules on the palate and the whole mouth, and the infected animal had to be removed at once from the herd, or the whole herd became infected. Gradually this distemper descended to the shoulders and thence to the feet, and in cases where this change took place almost all the animals were cured, but when it did not, they nearly always died. Now of these contagions which come from without, the air^? is the most potent cause, though they may also come from. water, marshes and other sources. 'The air is the most suit— able medium, partly because it very easily receives both its own and foreign infections, and because we have to use it to live. And we must not fail to observe that the air is sometimes mere— ly modified by becoming heated, or cooled, or drenched, or dried, but sometimes it not only alters thus, but also transmits to our bodies foreign vapors, which are themselves not 'simple,' but are also germs of contagions. Now the difference between & simple vapor and the germ of a contagion is that a vapor is a highly alterable thing made of a combination which is not strong and viscous, such as that of which the germ is made. Nevertheless, vapors that have been imported into our bodies concur in manifold ways to produce the putrefactions that arise therein. In the first place, they cause obstruction (of the humors), secondly they provide a locus for foreign heat and moisture, finally, when mingled with the humors, they make these hostile and unfriendly to the organs, from which they are rejected and abandoned by nature, and thus they putrefy. Germs however, not only do all this, but do it in the highest degree, and at the same time procreate other germs precisely similar to themselves, as progeny, which, when carried to an— other object, transmit the contagion to it. Accordingly, when the air carries into our bodies merely the simple vapors, that is not, so far, contagion, nor is the malady contagious per se, provided that there does not result a deep—