Book I CONTAGION 5 contagion; because contagion is a precisely similar infection of the actual substance. Now when a house catches fire from the burning of a neighboring house, are we to call that contagion? No, certainly not, nor in general when the whole thing is de— stroyed primarily as &a whole. 'The term is more correctly used when infection originates in very small imperceptible particles, and begins with them, as the word "infection' implies?; for we use the term ^infected', not of a something that is destroyed as a whole, but of a certain kind of destruction that affects its im— perceptible particles. By the whole, I mean the actual com— posite, and by very small, imperceptible particles, I mean the particles of which the composite and mixture (combination)3 are composed. Now burning acts on the thing as a whole, whereas contagion acts on the component particles, though by them the whole thing itself may presently be corrupted and destroyed. Contagion, then, seems to be a certain passive affection of elements in combination. But since such combinations can be corrupted and destroyed in two ways, either by the advent of a contrary element, owing to which the combination can— not retain its form, or secondly by the dissolution of the com— bination, as happens when things have putrefied, we may per— haps hestitate to say whether contagion, when it is carried in by infection of the smallest particles, is produced in the former way or the latter. Moreover, what shall we say is the nature of this infection? Is it a corruption of those particles, or only an alteration? What, in short, happens to those particles? Hence it is hard to determine whether every contagion is & kind of putrefaction. All these problems will become clearer if we first investigate the fundamental differences of contagions, and their causes. Meanwhile, if we allow ourselves to sketch a sort of tentative definition of contagion, we shall define it as: A certain precisely similar corruphton whch developes in the sub— sfance of a combination, passes from one thing to another, and 1s originally caused by infecthion of ihe «mperceptible particles.